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陈国颂
2014-06-19 | 【】【关闭

 

陈国颂 教授
上海市杨浦区淞沪路2005号 江湾化学-高分子楼B4080

电话:021-31244275

传真:021-31242888

邮箱:guosong@fudan.edu.cn

主页:http://www.polymer.fudan.edu.cn/polymer/research/CGSJM/CN/content.aspx?info_lb=28&flag=4

 

教育和工作经历

1997-2001

南开大学

化学学士

2001-2006

南开大学

物理化学博士

2006-2009

美国爱荷华州立大学化学系

有机化学博士后

2009-2011

复旦大学

讲 师

2011-2014

复旦大学

副教授 

2014-至今复旦大学教 授、博士生导师

 

研究兴趣

利用糖-蛋白质相互作用构筑蛋白质规则组装体和晶体

基于糖的大分子组装体的免疫学功能

糖化学反应驱动的大分子自组装

 

近年代表性论文

  1. Yufei Zhang, Libin Wu, Zhen Li, Weiyi Zhang, Feifei Luo, Yiwei Chu, Guosong Chen*, “Glycocalyx-Mimicking Nanoparticles Improve Anti-PD-L1 Cancer Immunotherapy through Reversion of Tumor-Associated Macrophages” Biomacromolecules 2018, 19, x.

  2. Libin Wu, Yufei Zhang, Zhen Li, Guang Yang, Zdravko Kochovski, Guosong Chen*, Ming Jiang, “"Sweet" Architecture-Dependent Uptake of Glycocalyx-Mimicking Nanoparticles Based on Biodegradable Aliphatic Polyesters by Macrophages” J. Am. Chem. Soc., 2017, 139, 14684-14692.

  3. Wei Zheng, Guang Yang, Nannan Shao, Li-Jun Chen, Bo Ou, Shu-Ting Jiang, Guosong Chen*, Haibo Yang*, “CO2 Stimuli-Responsive, Injectable Block Copolymer Hydrogels Cross-linked by Discrete Organoplatinum(II) Metallacycles via Stepwise Post-Assembly Polymerization”, J. Am. Chem. Soc., 2017, 139, 13811-13820.

  4. Guang Yang, Hong-ming Ding, Zdravko Kochovski, Rongting Hu, Yan Lu, Yu-qiang Ma*, Guosong Chen*, Ming Jiang “Highly ordered self-assembly of native proteins into 1D, 2D and 3D structures modulated by a tether length of inducing ligands”, Angew. Chem. Int. Ed. 2017, 56, 10691-10695.

  5. Yu Zhao, Yufei Zhang, Changchun Wang, Guosong Chen*, Ming Jiang, “Role of Protecting Groups in Synthesis and Self-Assembly of Glycopolymers”, Biomacromolecules 2017, 18, 568-575.

  6. Zhen Li, Liang Sun, Yufei Zhang, Andrew P Dove, Rachel K. O'Reilly*, Guosong Chen*, “Shape Effect of Glyco-Nanoparticles on Macrophage Uptake and Immune Response”, ACS Macro Lett., 2016, 5, 1059-0164.

  7. Yijiang Liu, Yufei Zhang, Zheyu Wang, Jue Wang, Kongchang Wei, Guosong Chen*, Ming Jiang, “Building Nanowires from Micelles: Hierarchical Self-assembly of Alternating Amphiphilic Glycopolypeptide Brushes with Pendants of High-Mannose Glycodendron and Oligophenylalanine”, J. Am Chem. Soc. 2016, 138, 12387-12394. 

  8. Guang Yang, Libin Wu, Guosong Chen*, Ming Jiang, “Precise Protein Assembly to Array Structures”, Chem. Commun. 2016, 52, 10595-10605.

  9. Zhongwei Ji, Junfang Li, Guosong Chen*, Ming Jiang, “Fate of Host-Stabilized Charge Transfer Complexation Based on Cucurbit[8]uril: Inducing Cyclization of PNIPAM and Dissociation in Self-Assembly of the Cyclic Polymer”, ACS Macro Lett. 2016, 5, 588-592.

  10. Wei Zheng, Li-Jun Chen, Guang Yang, Bin Sun, Xu Wang, Bo Jiang, Guang-Qiang Yin, Li Zhang, Xiaopeng Li, Minghua Liu, Guosong Chen*, Haibo Yang*, “Construction of Smart Supramolecular Polymeric Hydrogels Cross-linked by Discrete Organoplatinum(II) Metallacycles via Post-Assembly Polymerization”, J. Am. Chem. Soc., 2016, 138, 4927-4937.

  11. Guang Yang, Xiang Zhang, Zdravko Kochovski, Yufei Zhang, Bin Dai, Fuji Sakai, Lin Jiang, Yan Lu, Matthias Ballauff, Xueming Li, Cong Liu*, Guosong Chen*, Ming Jiang, “Precise and Reversible Protein-Microtubule-Like Structure with Helicity Driven by Dual Supramolecular Interactions”, J. Am. Chem. Soc., 2016, 138, 1932-1937.


 

主要荣誉与奖励

 中组部“万人计划”青年拔尖人才(2014)

 国家自然科学基金委优秀青年基金(2013)

上海市教委曙光计划(2013)

上海市科委青年科技启明星(A类)(2013)

    复旦大学卓学计划(2011)

    第6届冯新德高分子奖(与江明教授共享)

    南开大学研究生特等奖学金

    第十八届诺贝尔奖获得者大会参加奖(国家自然科学基金委和德国DFG联合选拔)

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